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optical genome mapping bionano genomics irys system  (BioNano Genomics)

 
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    BioNano Genomics optical genome mapping bionano genomics irys system
    Optical Genome Mapping Bionano Genomics Irys System, supplied by BioNano Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/optical genome mapping bionano genomics irys system/product/BioNano Genomics
    Average 90 stars, based on 1 article reviews
    optical genome mapping bionano genomics irys system - by Bioz Stars, 2026-05
    90/100 stars

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    Schematic overview of the DNA fiber approach to analyze distinct replication events. Two subsequent pulses of the thymidine analogs IdU (5-iodo-2–deoxy-uridine) and CldU (5-chloro-2-deoxy-uridine) are used to label active DNA synthesis. (A) Study of replication initiation, elongation, and termination events. (B) Determining the distance between two neighboring replication origins. (C) Investigating the effect of genotoxic stress-inducing agents on replication progression.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Single-Molecule Techniques to Study Chromatin

    doi: 10.3389/fcell.2021.699771

    Figure Lengend Snippet: Schematic overview of the DNA fiber approach to analyze distinct replication events. Two subsequent pulses of the thymidine analogs IdU (5-iodo-2–deoxy-uridine) and CldU (5-chloro-2-deoxy-uridine) are used to label active DNA synthesis. (A) Study of replication initiation, elongation, and termination events. (B) Determining the distance between two neighboring replication origins. (C) Investigating the effect of genotoxic stress-inducing agents on replication progression.

    Article Snippet: For example, an optical DNA mapping device (Bionano Genomics Irys) was repurposed to visualize DNA replication in Xenopus laevis egg extracts ( ).

    Techniques: DNA Synthesis